American Foundation for the Blind
http://www.afb.org
Provides resource information about agencies throughout the United States and Canada serving the needs of people who are visually impaired or blind

The Foundation Fighting Blindness
http://www.blindness.org
Provides information, referrals and support for people who are visually impaired or blind.  Very active in tracking and supporting research and treatment of eye diseases.

The Guild for the Blind
http://www.guildfortheblind.org
The Guild for the Blind works with adults who are blind or visually impaired, providing them with the tools and training they need to live independently and with dignity. A complete list of their programs and services can be found on their web site.

VisionConnection
http://www.visionconnection.org/VisionConnection.org
VisionConnection is the new one-stop fully accessible and interactive global Internet portal for people who are blind or partially sighted, the professionals who serve them, their families and friends who support them -- and anyone looking for the latest information on vision impairments, its prevention and vision rehabilitation.